Chromosome evolution of Escherichia coli Nissle 1917 for high‐level production of heparosan
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DOI: 10.1002/bit.28315
Abstract: Heparosan is a crucial‐polysaccharide precursor for the chemoenzymatic synthesis of heparin, a widely used anticoagulant drug. Presently, heparosan is mainly extracted with the potential risk of contamination from Escherichia coli strain K5, a pathogenic bacterium… read more here.
Keywords: nissle 1917; chromosome evolution; escherichia coli; kps locus ... See more keywords