KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals
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DOI: 10.1038/s41467-021-24739-9
Abstract: Regulation of IP3 receptors (IP3Rs) by IP3 and Ca2+ allows regenerative Ca2+ signals, the smallest being Ca2+ puffs, which arise from coordinated openings of a few clustered IP3Rs. Cells express thousands of mostly mobile IP3Rs,… read more here.
Keywords: ca2 signals; krap tethers; ca2 puffs; ca2 ... See more keywords