Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.3c00920
Abstract: The RAS-transformed cells utilize macropinocytosis to acquire amino acids to support their uncontrolled growth. However, targeting RAS to inhibit macropinocytosis remains a challenge. Here, we report that gold nanoparticles (GNP) inhibit macropinocytosis by decreasing KRAS… read more here.
Keywords: inhibit macropinocytosis; macropinocytosis decreasing; gold nanoparticles; kras activation ... See more keywords
Abstract 1392: Development of a novel mouse model for intrahepatic cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-1392
Abstract: Cholangiocarcinoma (CCA) is a poorly understood cancer of the biliary epithelium and the second most common type of liver cancer. Surgery currently offers the only potential for cure; however, most patients present with advanced disease… read more here.
Keywords: kras activation; bap1; intrahepatic cholangiocarcinoma; cancer ... See more keywords