RAGE maintains high levels of NFκB and oncogenic Kras activity in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.08.147
Abstract: Oncogenic KRas activity is central to several cancer types including pancreatic ductal adenocarcinoma (PDAC) but has been determined to be "undruggable". Recent studies have indicated that oncogenic KRas is not constitutively active but relies on… read more here.
Keywords: pdac; oncogenic kras; rage; cancer ... See more keywords