Concurrent activation of Kras and canonical Wnt signaling induces premalignant lesions that progress to extrahepatic biliary cancer in mice.
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DOI: 10.1158/0008-5472.can-21-2176
Abstract: Biliary cancer has long been known to carry a poor prognosis, yet the molecular pathogenesis of carcinoma of the extrahepatic biliary system and its precursor lesions remains elusive. Here we investigated the role of Kras… read more here.
Keywords: canonical wnt; cancer; biliary cancer; kras canonical ... See more keywords