Articles with "kras erk" as a keyword



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Mutant Kras and mTOR crosstalk drives hepatocellular carcinoma development via PEG3/STAT3/BEX2 signaling

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Published in 2022 at "Theranostics"

DOI: 10.7150/thno.76873

Abstract: Background & Aims: Abnormal activation of mTOR through loss of tuberous sclerosis complex (Tsc) frequently occurs in hepatocellular carcinoma (HCC). Mutant Kras could induce aggressive HCCs. Here, we aim to identify the predictive or prognostic… read more here.

Keywords: hepatocellular carcinoma; kras erk; peg3; hcc ... See more keywords