Association between KRAS gene polymorphisms and genetic susceptibility to breast cancer in a Chinese population
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24806
Abstract: The KRAS gene has a pathophysiological role in the development of many cancers. This study aims to investigate the relationship between KRAS polymorphisms and genetic susceptibility to breast cancer. read more here.
Keywords: susceptibility breast; genetic susceptibility; breast cancer; kras gene ... See more keywords
In Silico Analysis of nsSNPs of Human KRAS Gene and Protein Modeling Using Bioinformatic Tools
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c00804
Abstract: The KRAS gene belongs to the RAS family and codes for 188 amino acid residues of KRAS protein, with a molecular mass of 21.6 kD. Non-synonymous single-nucleotide polymorphisms (nsSNPs) have been identified within the coding… read more here.
Keywords: analysis nssnps; bioinformatic tools; kras gene; silico analysis ... See more keywords
The value of KRAS gene status in predicting local tumor progression of colorectal liver metastases following radiofrequency ablation
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hyperthermia"
DOI: 10.1080/02656736.2018.1556818
Abstract: Abstract Purpose: We investigated the relationships between KRAS gene status and local tumor progression (LTP) of colorectal liver metastases (CLMs) after treatment with percutaneous ultrasound-guided radiofrequency ablation (RFA). Materials and methods: Clinical and imaging data… read more here.
Keywords: liver metastases; gene; kras gene; gene status ... See more keywords
Discovery of a novel and a rare Kristen rat sarcoma viral oncogene homolog (KRAS) gene mutation in colorectal cancer patients.
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.1960715
Abstract: Colorectal cancer (CRC) is one of the most important causes of morbidity and mortality in the developed world and is gradually more frequent in the developing world including Saudi Arabia. According to the Saudi Cancer… read more here.
Keywords: kras gene; colorectal cancer; discovery novel; cancer ... See more keywords
Abstract 671: Prognostic importance of EGFR expression and Kras gene mutations in gallbladder carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-671
Abstract: Gallbladder carcinomas involve multiple cascades of oncogenes like EGFR and Kras. Activation of Kras downstream pathways predict the sensitivity to anti EGFR treatment. In 2012, for the first time it was established that GBC and… read more here.
Keywords: kras gene; expression; egfr expression; prognostic importance ... See more keywords
Frequency of somatic mutations in the KRAS gene in patients of the South Russia diagnosed with colorectal cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e15081
Abstract: e15081 Background: Colorectal cancer (CRC) is a common pathology in the world; the annual incidence rate reaches 1 million cases, and the annual mortality rate exceeds 500,000. The target therapy of EGFR with monoclonal drugs… read more here.
Keywords: kras gene; somatic mutations; south russia; gene ... See more keywords
Relationship between PET/CT images and KRAS gene mutations in colorectal cancer in Vietnamese patients.
Sign Up to like & getrecommendations! Published in 2023 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202302_31388
Abstract: OBJECTIVE We conducted this study to determine the relationship among standardized uptake value (SUV), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) indexes of Flourine-18 fluorodeoxyglucose positron emission tomography/computed tomography18 (FDG-PET/CT) imaging and Kirsten… read more here.
Keywords: relationship; suvmax; value; kras gene ... See more keywords
PATTERN OF KRAS GENE EXPRESSION IN IRAQI WOMEN OVARIAN CARCINOMA.
Sign Up to like & getrecommendations! Published in 2022 at "Wiadomosci lekarskie"
DOI: 10.36740/wlek202204103
Abstract: OBJECTIVE The aim: The goal of this study was to detect if KRAS gene and levels of had any clinical significance in the ovarian cancer by measuring levels of KRAS mRNA. PATIENTS AND METHODS Materials… read more here.
Keywords: ovarian cancer; expression; kras gene; kras mrna ... See more keywords