Activating KRAS and GNAS mutations in heterotopic submucosal glands of the stomach
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-022-01863-x
Abstract: The heterotopic submucosal gland (HSG) is a common incidental finding in gastrectomy specimens. The majority of HSGs are small incidental lesions, which are also known as gastritis cystica profunda. However, larger lesions may appear as… read more here.
Keywords: hsg lesions; activating kras; mutations heterotopic; kras gnas ... See more keywords
GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling.
Sign Up to like & getrecommendations! Published in 2018 at "Gastroenterology"
DOI: 10.1053/j.gastro.2018.08.006
Abstract: BACKGROUND & AIMS Mutations at hotspots in GNAS, which encodes stimulatory G-protein, α subunits, are detected in approximately 60% of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. We generated mice with KRAS-induced IPMNs that… read more here.
Keywords: mice express; activated kras; kras gnas; mice ... See more keywords