Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited anti-tumor activity.
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DOI: 10.1182/blood.2020010572
Abstract: The multiple myeloma (MM) mutational landscape has identified alterations in KRAS as the most recurring somatic variant. Combining DNA and RNA sequencing, we studied 756 patients and observed KRAS as the most frequently mutated gene… read more here.
Keywords: mutational landscape; myeloma; targeting kras; kras mutational ... See more keywords