Articles with "kras supports" as a keyword



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Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-07472-8

Abstract: Oncogenic KRAS is the key driver of pancreatic ductal adenocarcinoma (PDAC). We previously described a role for KRAS in PDAC tumor maintenance through rewiring of cellular metabolism to support proliferation. Understanding the details of this… read more here.

Keywords: pdac; oncogenic kras; kras supports; kras resistant ... See more keywords