KRAS mutation-induced EndMT of brain arteriovenous malformation is mediated through the TGF-β/BMP-SMAD4 pathway
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DOI: 10.1136/svn-2022-001700
Abstract: Objective Somatic KRAS mutations have been identified in the majority of brain arteriovenous malformations (bAVMs), and subsequent in vivo experiments have confirmed that KRAS mutation in endothelial cells (ECs) causes AVMs in mouse and zebrafish… read more here.
Keywords: krasg12d; krasg12d mutant; brain arteriovenous; tgf bmp ... See more keywords