vFLIP-regulated competing endogenous RNA (ceRNA) networks targeting lytic induction for KSHV-associated malignancies.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medical virology"
DOI: 10.1002/jmv.27654
Abstract: Kaposi's sarcoma-associated herpesvirus (KSHV) causes life-long latent infection and malignancies, including Kaposi sarcoma (KS) commonly found in AIDS patients. Lytic replication can be induced to kill tumor cells harboring latent KSHV, through viral cytopathic effects… read more here.
Keywords: associated malignancies; cerna networks; mir; kshv associated ... See more keywords
Characteristics and outcomes of KSHV-associated multicentric Castleman disease with or without other KSHV diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2020004058
Abstract: Kaposi sarcoma (KS)-associated herpesvirus (KSHV)-associated multicentric Castleman disease (MCD) is a relapsing and remitting systemic lymphoproliferative disorder characterized by severe inflammatory symptoms most common among people living with HIV (PLWH). Patients with KSHV-MCD may present… read more here.
Keywords: kshv associated; kshv; kshv mcd; associated multicentric ... See more keywords
Molecular Virology of KSHV in the Lymphocyte Compartment—Insights From Patient Samples and De Novo Infection Models
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.607663
Abstract: The incidence of Kaposi’s sarcoma-associated herpesvirus (KSHV)-associated Kaposi Sarcoma has declined precipitously in the present era of effective HIV treatment. However, KSHV-associated lymphoproliferative disorders although rare, have not seen a similar decline. Lymphoma is now… read more here.
Keywords: kshv associated; virology; infection; lymphocyte compartment ... See more keywords