CXCL1 confers a survival advantage in Kaposi's sarcoma‐associated herpesvirus‐infected human endothelial cells through STAT3 phosphorylation
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DOI: 10.1002/jmv.28020
Abstract: Many cytokines produced by Kaposi's sarcoma‐associated herpesvirus (KSHV)‐infected cells have been shown to participate in the pathogenesis of KSHV. Determination of the exact role of cytokines in Kaposi's sarcoma (KS) pathogenesis is limited, however, by… read more here.
Keywords: kshv infected; cxcl1; endothelial cells; kshv ... See more keywords
LANA regulates miR‐155/GATA3 signaling axis by enhancing c‐Jun/c‐Fos interaction to promote the proliferation and migration of KSHV‐infected cells
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DOI: 10.1002/jmv.28255
Abstract: Kaposi's sarcoma (KS) is the second most common tumor in people infected with human immunodeficiency virus worldwide, but its pathogenesis is still unclear. In this study, we discovered that the expression of GATA‐binding protein 3… read more here.
Keywords: mir 155; kshv infected; jun fos; infected cells ... See more keywords
Lack of CD8+ T-cell co-localization with Kaposi’s sarcoma-associated herpesvirus infected cells in Kaposi’s sarcoma tumors
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DOI: 10.18632/oncotarget.27569
Abstract: Despite the close association between Kaposi’s sarcoma (KS) and immune dysfunction, it remains unclear whether tumor infiltrating immune cells (TIIC), by their absence, presence, or dysfunction, are mechanistically correlated with KS pathogenesis. Therefore, their potential… read more here.
Keywords: kaposi sarcoma; cell; kshv infected; infected cells ... See more keywords
Synthetic antioxidants from a natural source can overtake the oncogenic stress management system and activate the stress-sensitized death of KSHV-infected cancer cells
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DOI: 10.3892/ijmm.2022.5173
Abstract: Synthetic and modified natural derivatives are reported as potential bioactive compounds and are being used therapeutically against various diseases in a wide-spread manner nowadays. Cancerous cells exhibit high levels of reactive oxygen species (ROS) internally,… read more here.
Keywords: kshv infected; stress; oncogenic stress; stress management ... See more keywords
miR-34a-5p inhibits the malignant progression of KSHV-infected SH-SY5Y cells by targeting c-fos
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DOI: 10.7717/peerj.13233
Abstract: Background We aimed to investigate the effects of miR-34a-5p on c-fos regulation mediating the malignant behaviors of SH-SY5Y cells infected with Kaposi’s sarcoma-associated herpesvirus (KSHV). Methods The KSHV-infected (SK-RG) and uninfected SH-SY5Y parent cells were… read more here.
Keywords: fos mir; sy5y cells; mir 34a; kshv infected ... See more keywords