Going beyond Binary: Rapid Identification of Protein-Protein Interaction Modulators Using a Multifragment Kinetic Target-Guided Synthesis Approach.
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DOI: 10.1021/acs.jmedchem.3c00108
Abstract: Kinetic target-guided synthesis (KTGS) is a powerful screening approach that enables identification of small molecule modulators for biomolecules. While many KTGS variants have emerged, a majority of the examples suffer from limited throughput and a… read more here.
Keywords: ktgs; guided synthesis; kinetic target; target guided ... See more keywords