Genitourinary involvement in pediatric patients with Klippel-Trenaunay Syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical imaging"
DOI: 10.1016/j.clinimag.2020.06.011
Abstract: BACKGROUND Klippel-Trenaunay Syndrome (KTS) is a genetic vascular malformation disorder which induces a variety of phenotypic expression in patients which differ in terms of severity/location. While previous studies have documented genitourinary (GU) complications in adult… read more here.
Keywords: involvement pediatric; age; klippel trenaunay; kts ... See more keywords
RNA Binding by the KTS Splice Variants of the Wilms' Tumor Suppressor Protein WT1.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00602
Abstract: The Wilms' tumor suppressor protein WT1 regulates the expression of multiple genes through binding of the Cys2-His2 zinc-finger domain to promoter sites. WT1 has also been proposed to be involved in post-transcriptional regulation, by binding… read more here.
Keywords: zinc; splice variants; kts; wt1 ... See more keywords
The Kampala Trauma Score: A 20-year track record
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000003567
Abstract: 20 years ago, this journal published a paper titled that detailed the development of the ‘Kampala Trauma Score’, a new injury severity score. This review is the first of its kind to explore the 20-year… read more here.
Keywords: injury severity; trauma; kts; trauma score ... See more keywords
Klippel-Trenaunay syndrome or not? An exploration of atypical presentations
Sign Up to like & getrecommendations! Published in 2024 at "BMJ Case Reports"
DOI: 10.1136/bcr-2024-259763
Abstract: Klippel-Trenaunay syndrome (KTS) is a rare, congenital disorder typically emerging in early infancy or childhood. The classic presentation of KTS is distinguished by a triad of clinical features: a port-wine stain, early-onset varicosities and limb… read more here.
Keywords: trenaunay syndrome; atypical presentations; klippel trenaunay; syndrome exploration ... See more keywords
The First Snake Venom KTS/Disintegrins-Integrin Interactions Using Bioinformatics Approaches
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DOI: 10.3390/molecules28010325
Abstract: Snake venom contains a number of active molecules that have been shown to possess high anti-tumor activities; disintegrins are an excellent example among these. Their ability to interact and bind with integrins suggests that they… read more here.
Keywords: kts disintegrins; bioinformatics approaches; disintegrins integrin; kts ... See more keywords
RETRACTED: Structure–Activity Relationship of Synthetic Linear KTS-Peptides Containing Meta-Aminobenzoic Acid as Antagonists of α1β1 Integrin with Anti-Angiogenic and Melanoma Anti-Tumor Activities
Sign Up to like & getrecommendations! Published in 2024 at "Pharmaceuticals"
DOI: 10.3390/ph17050549
Abstract: To develop peptide drugs targeting integrin receptors, synthetic peptide ligands endowed with well-defined selective binding motifs are necessary. The snake venom KTS-containing disintegrins, which selectively block collagen α1β1 integrin, were used as lead compounds for… read more here.
Keywords: aminobenzoic acid; structure activity; peptides containing; peptide ... See more keywords