Inhibition of glycolysis by a novel EGFR/HER2 inhibitor KU004 suppresses the growth of HER2+ cancer
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DOI: 10.1016/j.yexcr.2017.05.019
Abstract: &NA; Upregulation of glycolysis was often observed in human HER2‐overexpressing cancers. In this study, we demonstrated that KU004, a dual novel EGFR/HER2 inhibitor, disrupted cancer cell proliferation via modulation of glycolysis. KU004, inhibited the Warburg… read more here.
Keywords: egfr her2; ku004; glycolysis; novel egfr ... See more keywords