Super-resolution imaging identifies PARP1 and the Ku complex acting as DNA double-strand break sensors
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DOI: 10.1093/nar/gky088
Abstract: Abstract DNA double-strand breaks (DSBs) are fatal DNA lesions and activate a rapid DNA damage response. However, the earliest stage of DSB sensing remains elusive. Here, we report that PARP1 and the Ku70/80 complex localize… read more here.
Keywords: ku70 complex; dsb; dna; dna double ... See more keywords