Articles with "ku80" as a keyword



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Cloning of canine Ku80 and its localization and accumulation at DNA damage sites

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Published in 2017 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12311

Abstract: Molecularly targeted therapies have high specificity and significant cancer‐killing effect. However, their antitumor effect might be greatly diminished by variation in even a single amino acid in the target site, as it occurs, for example,… read more here.

Keywords: dna; canine ku80; ku80; cloning canine ... See more keywords
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Ku80 promotes melanoma growth and regulates antitumor effect of melatonin by targeting HIF1-α dependent PDK-1 signaling pathway

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Published in 2019 at "Redox Biology"

DOI: 10.1016/j.redox.2019.101197

Abstract: Melanoma is one of the most malignant and aggressive cancers with high cancer-related deaths. However, it is unclear whether Ku80 regulates tumor growth in human melanoma. In this study, we screened a siRNA library targeting… read more here.

Keywords: melanoma; melanoma growth; pdk; ku80 ... See more keywords