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Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0704-6_1
Abstract: Kupffer cells and hepatocytes maintain liver homeostasis. These cells could be separated based on their size and weight, by centrifugation using a density gradient after a liver perfusion. Here, we describe a methodology to isolate…
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Keywords:
single mouse;
kupffer;
liver;
centrifugation ... See more keywords
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Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0704-6_4
Abstract: Kupffer cells are the majority of tissue macrophages present in the body and are actively involved in the regulation of liver homeostasis as well as in the progression of liver diseases. Here we describe a…
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Keywords:
kupffer;
protein isolation;
kupffer cell;
cell ... See more keywords
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Published in 2021 at "Biomaterials science"
DOI: 10.1039/d1bm01663f
Abstract: Liver fibrosis therapy remains limited due to the inefficiency of drug delivery and inflammation induced by Kupffer cells. In this study, an exosome-liposome hybrid drug delivery system (LIEV) was developed to increase the efficacy of…
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Keywords:
liver fibrosis;
fibrosis therapy;
kupffer;
nin ... See more keywords
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Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010693
Abstract: Polysaccharide capsule is the main virulence factor of K. pneumoniae, a major pathogen of bloodstream infections in humans. While more than 80 capsular serotypes have been identified in K. pneumoniae, only several serotypes are frequently…
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Keywords:
liver;
pneumoniae;
virulence;
capture ... See more keywords
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Published in 2018 at "Life Science Alliance"
DOI: 10.26508/lsa.201800111
Abstract: This study reports on the identification of two Plasmodium GAPDH epitope peptides that are responsible for sporozoite–Kupffer cell interaction and act as antigens against malaria infection. Plasmodium sporozoite liver infection is an essential step for…
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Keywords:
kupffer;
infection;
plasmodium gapdh;
identification ... See more keywords
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Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.726931
Abstract: Background: There has been a recent appreciation that some metabolic enzymes can profoundly influence the nature of the immune response produced in macrophages. However, the role of mitochondrial phosphoenolpyruvate carboxykinase (PCK2) in immune response remains…
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Keywords:
response kupffer;
function;
kupffer;
kupffer cells ... See more keywords
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Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.811164
Abstract: Traumatic hemorrhagic shock (THS) is a major cause of mortality and morbidity worldwide in severely injured patients. Mesenchymal stem cells (MSCs) possess immunomodulatory properties and tissue repair potential mainly through a paracrine pathway mediated by…
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Keywords:
traumatic hemorrhagic;
injury;
kupffer;
hepatic injury ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.892114
Abstract: Kupffer cells are the primary liver resident immune cell responsible for the liver firewall function, including clearance of bacterial infection from the circulation, as they are strategically positioned inside the liver sinusoid with intimate contact…
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Keywords:
cell;
liver injury;
kupffer cells;
niche ... See more keywords