Articles with "kupffer" as a keyword



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Kupffer Cell and Hepatocyte Isolation from a Single Mouse Liver by Gradient Centrifugation.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0704-6_1

Abstract: Kupffer cells and hepatocytes maintain liver homeostasis. These cells could be separated based on their size and weight, by centrifugation using a density gradient after a liver perfusion. Here, we describe a methodology to isolate… read more here.

Keywords: single mouse; kupffer; liver; centrifugation ... See more keywords
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Kupffer Cell Protein Isolation and Detection by Western Blot.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0704-6_4

Abstract: Kupffer cells are the majority of tissue macrophages present in the body and are actively involved in the regulation of liver homeostasis as well as in the progression of liver diseases. Here we describe a… read more here.

Keywords: kupffer; protein isolation; kupffer cell; cell ... See more keywords
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Clodronate-nintedanib-loaded exosome-liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity.

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Published in 2021 at "Biomaterials science"

DOI: 10.1039/d1bm01663f

Abstract: Liver fibrosis therapy remains limited due to the inefficiency of drug delivery and inflammation induced by Kupffer cells. In this study, an exosome-liposome hybrid drug delivery system (LIEV) was developed to increase the efficacy of… read more here.

Keywords: liver fibrosis; fibrosis therapy; kupffer; nin ... See more keywords
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Capsule type defines the capability of Klebsiella pneumoniae in evading Kupffer cell capture in the liver

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Published in 2022 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1010693

Abstract: Polysaccharide capsule is the main virulence factor of K. pneumoniae, a major pathogen of bloodstream infections in humans. While more than 80 capsular serotypes have been identified in K. pneumoniae, only several serotypes are frequently… read more here.

Keywords: liver; pneumoniae; virulence; capture ... See more keywords
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Identification of Plasmodium GAPDH epitopes for generation of antibodies that inhibit malaria infection

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Published in 2018 at "Life Science Alliance"

DOI: 10.26508/lsa.201800111

Abstract: This study reports on the identification of two Plasmodium GAPDH epitope peptides that are responsible for sporozoite–Kupffer cell interaction and act as antigens against malaria infection. Plasmodium sporozoite liver infection is an essential step for… read more here.

Keywords: kupffer; infection; plasmodium gapdh; identification ... See more keywords
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A Novel Function of Mitochondrial Phosphoenolpyruvate Carboxykinase as a Regulator of Inflammatory Response in Kupffer Cells

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.726931

Abstract: Background: There has been a recent appreciation that some metabolic enzymes can profoundly influence the nature of the immune response produced in macrophages. However, the role of mitochondrial phosphoenolpyruvate carboxykinase (PCK2) in immune response remains… read more here.

Keywords: response kupffer; function; kupffer; kupffer cells ... See more keywords
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Mesenchymal Stem Cells Derived Extracellular Vesicles Alleviate Traumatic Hemorrhagic Shock Induced Hepatic Injury via IL-10/PTPN22-Mediated M2 Kupffer Cell Polarization

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.811164

Abstract: Traumatic hemorrhagic shock (THS) is a major cause of mortality and morbidity worldwide in severely injured patients. Mesenchymal stem cells (MSCs) possess immunomodulatory properties and tissue repair potential mainly through a paracrine pathway mediated by… read more here.

Keywords: traumatic hemorrhagic; injury; kupffer; hepatic injury ... See more keywords
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Susceptibility to Infections During Acute Liver Injury Depends on Transient Disruption of Liver Macrophage Niche

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.892114

Abstract: Kupffer cells are the primary liver resident immune cell responsible for the liver firewall function, including clearance of bacterial infection from the circulation, as they are strategically positioned inside the liver sinusoid with intimate contact… read more here.

Keywords: cell; liver injury; kupffer cells; niche ... See more keywords