Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels
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DOI: 10.1007/s12035-017-0437-2
Abstract: Inhalational general anesthetics, such as sevoflurane and isoflurane, modulate a subset of brain Kv1 potassium channels. However, the Kv1.2 channel is resistant to propofol, a commonly used intravenous alkylphenol anesthetic. We hypothesize that propofol binds… read more here.
Keywords: kv1; modulation; propofol; kv1 g329t ... See more keywords