Pi(4,5)P2 Modulates Hysteresis and Pharmacology of KV7 Channels
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DOI: 10.1016/j.bpj.2016.11.624
Abstract: KV7 channels are critical components of the plasma membrane in many excitable cells. The main function of KV7 channels is to contribute to the maintenance of the resting potential, thus regulating cellular electrical excitability. In… read more here.
Keywords: kv7 kv7; kv7; pharmacology; hysteretic behavior ... See more keywords
Inhibition of Kv7/M Channel Currents by Fangchinoline
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DOI: 10.1159/000527464
Abstract: Introduction: Voltage-gated Kv7/M potassium channels play an essential role in the control of membrane potential and neuronal excitability. Fangchinoline, a bisbenzylisoquinoline alkaloid, displays extensive biological activities including antitumor, anti-inflammatory, and antihypertension effects. In this study,… read more here.
Keywords: channel currents; kv7; kv7 channels; kv7 channel ... See more keywords