Immunomodulatory actions of a kynurenine-derived endogenous electrophile
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DOI: 10.1101/2022.02.08.479451
Abstract: The inflammatory upregulation of kynurenine metabolism induces immunomodulatory responses via incompletely understood mechanisms. We report that increases in cellular and systemic kynurenine levels yield the electrophilic derivative kynurenine-carboxyketoalkene (Kyn-CKA), as evidenced by the accumulation of… read more here.
Keywords: kyn cka; immunomodulatory actions; kynurenine; kynurenine derived ... See more keywords