Articles with "kynurenine aminotransferase" as a keyword



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Fragment Screening of Human Kynurenine Aminotransferase-II

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Published in 2018 at "SLAS Discovery"

DOI: 10.1177/2472555218764620

Abstract: Kynurenine aminotransferase-II (KAT-II) is a pyridoxal 5′-phosphate (PLP)–dependent enzyme that acts in the tryptophan metabolic pathway by catalyzing the transamination of kynurenine into kynurenic acid (KYNA). It is one of four isoforms in the KAT… read more here.

Keywords: kynurenine; kynurenine aminotransferase; fragment screening; screening human ... See more keywords