Genome‐wide detection of ultralow‐frequency substitution mutations in cultures of mouse lymphoma L5178Y cells and Caenorhabditis elegans worms by PacBio sequencing
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DOI: 10.1002/em.22473
Abstract: Many conventional genetic toxicology assays require specialized cell cultures or animals and can only detect mutations that inactivate the function of a reporter gene. These limitations make such assays incompatible with many toxicological models but… read more here.
Keywords: elegans worms; pacbio sequencing; genome wide; detection ... See more keywords