Potent and durable control of mesothelin-expressing tumors by a novel T cell-secreted bi-specific engager
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DOI: 10.1136/jitc-2024-010063
Abstract: Background The glycosylphosphatidylinositol-anchored cell surface protein mesothelin (MSLN) shows elevated expression in many malignancies and is an established clinical-stage target for antibody-directed therapeutic strategies. Of these, the harnessing of autologous patient T cells via engineered… read more here.
Keywords: anti msln; labc 13f08; cell secreted; msln ... See more keywords