The key role of ergothioneine in label‐free surface‐enhanced Raman scattering spectra of biofluids: a retrospective re‐assessment of the literature
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14312
Abstract: Label‐free surface‐enhanced Raman scattering (SERS) has recently gained attention in the field of liquid biopsy as a rapid and relatively inexpensive technique that could significantly ease clinical diagnosis and prognosis by investigating a biofluid sample… read more here.
Keywords: label free; role; surface enhanced; ergothioneine ... See more keywords
Ultrahigh-Sensitivity Sandwiched Plasmon Ruler for Label-Free Clinical Diagnosis.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201905927
Abstract: Optical biosensors, especially those based on plasmonic structures, have emerged recently as a potential tool for disease diagnostics. Plasmonic biosensors have demonstrated impressive benefits for the label-free detection of trace biomarkers in human serum. However,… read more here.
Keywords: sandwiched plasmon; sensitivity; label free; ultrahigh sensitivity ... See more keywords
Immune Profiling and Multiplexed Label‐Free Detection of 2D MXenes by Mass Cytometry and High‐Dimensional Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202205154
Abstract: There is a critical unmet need to detect and image 2D materials within single cells and tissues while surveying a high degree of information from single cells. Here, a versatile multiplexed label‐free single‐cell detection strategy… read more here.
Keywords: label free; cell; mass cytometry; multiplexed label ... See more keywords
Plasmonic Dual‐Gap Nanodumbbells for Label‐Free On‐Particle Raman DNA Assays
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202208250
Abstract: Metal nanostructures with a tunable plasmonic gap are useful for photonics, surface‐enhanced spectroscopy, biosensing, and bioimaging applications. The use of these structures as chemical and biological sensing/imaging probes typically requires an ultra‐precise synthesis of the… read more here.
Keywords: label free; dual gap; gap nanodumbbells; gap ... See more keywords
Ultra‐Fast Label‐Free Serum Metabolic Diagnosis of Coronary Heart Disease via a Deep Stabilizer
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202101333
Abstract: Abstract Although mass spectrometry (MS) of metabolites has the potential to provide real‐time monitoring of patient status for diagnostic purposes, the diagnostic application of MS is limited due to sample treatment and data quality/reproducibility. Here,… read more here.
Keywords: diagnosis; ultra fast; deep stabilizer; fast label ... See more keywords
A Versatile, Incubator‐Compatible, Monolithic GaN Photonic Chipscope for Label‐Free Monitoring of Live Cell Activities
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202200910
Abstract: The ability to quantitatively monitor various cellular activities is critical for understanding their biological functions and the therapeutic response of cells to drugs. Unfortunately, existing approaches such as fluorescent staining and impedance‐based methods are often… read more here.
Keywords: label free; cell; chipscope; cell activities ... See more keywords
Real‐Time and Label‐Free Measurement of Deubiquitinase Activity with a MspA Nanopore
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100092
Abstract: Covalently attaching ubiquitin (Ub) to cellular proteins as a post‐translational modification can result in altered function of modified proteins. Enzymes regulating Ub as a post‐translational modification, such as ligases and deubiquitinases, are challenging to characterize… read more here.
Keywords: real time; label free; mspa; activity ... See more keywords
Desorption Electrospray Ionization Mass Spectrometry Assay for Label‐Free Characterization of SULT2B1b Enzyme Kinetics
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200043
Abstract: The sulfotransferase (SULT) 2B1b, which catalyzes the sulfonation of 3β‐hydroxysteroids, has been identified as a potential target for prostate cancer treatment. However, a major limitation for SULT2B1b‐targeted drug discovery is the lack of robust assays… read more here.
Keywords: label free; sult2b1b; mass spectrometry; desorption electrospray ... See more keywords
Interactions between Caffeine, Theophylline and Derivatives with Gold Nanoparticles and Implications for Aptamer-Based Label-Free Colorimetric Detection.
Sign Up to like & getrecommendations! Published in 2022 at "ChemPlusChem"
DOI: 10.1002/cplu.202200265
Abstract: Caffeine, theophylline, and other methylxanthines have interesting biological activities and are consumed in high quantities globally, causing health and environmental concerns. Gold nanoparticles (AuNPs) have excellent optical properties for biosensor development, although little is known… read more here.
Keywords: label free; adsorption; gold nanoparticles; caffeine theophylline ... See more keywords
Development of a New Label‐free, Indicator‐free Strategy toward Ultrasensitive Electrochemical DNA Biosensing Based on Fe3O4 Nanoparticles/Reduced Graphene Oxide Composite
Sign Up to like & getrecommendations! Published in 2017 at "Electroanalysis"
DOI: 10.1002/elan.201600336
Abstract: Electrochemistry offers sensitivity, selectivity and low cost for fabrication of sensors capable of detection of selected DNA targets or mutated genes associated with human disease. In this work, we have developed a novel label-free, indicator-free… read more here.
Keywords: dna; free strategy; indicator free; label free ... See more keywords
Label‐free Voltammetric Immunosensor for Prostate Specific Antigen Detection
Sign Up to like & getrecommendations! Published in 2018 at "Electroanalysis"
DOI: 10.1002/elan.201800417
Abstract: This work describes a sensitive voltammetric immunosensor for label-free electroanalysis of the prostate specific antigen (PSA), the main biomarker of prostate cancer. A gold electrode was firstly modified with the optimum self-assembled monolayer (SAM), 1,6hexanedithiol,… read more here.
Keywords: detection; prostate specific; immunosensor; voltammetric immunosensor ... See more keywords