The key role of ergothioneine in label‐free surface‐enhanced Raman scattering spectra of biofluids: a retrospective re‐assessment of the literature
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14312
Abstract: Label‐free surface‐enhanced Raman scattering (SERS) has recently gained attention in the field of liquid biopsy as a rapid and relatively inexpensive technique that could significantly ease clinical diagnosis and prognosis by investigating a biofluid sample… read more here.
Keywords: label free; role; surface enhanced; ergothioneine ... See more keywords
Topological Engineering of Exceptional Points for Label‐Free Single‐Molecule Detection
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202511772
Abstract: The topological structures around exceptional points (EPs) exhibit enhanced sensitivity for label‐free biosensors. However, the challenge of modifying the intrinsic topology to increase EP biosensor sensitivity remains unresolved. Here, topologically engineered EPs are utilized in… read more here.
Keywords: detection; exceptional points; topology; sensitivity ... See more keywords
Emerging 2D Materials and Their Hybrid Nanostructures for Label‐Free Optical Biosensing: Recent Progress and Outlook
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202513767
Abstract: The increasing demand for rapid detection and remote monitoring with high sensitivity and selectivity has driven the development of label‐free optical biosensors based on 2D materials (2DMs). Owing to their high surface‐to‐volume ratio and unique,… read more here.
Keywords: recent progress; hybrid nanostructures; biosensing; free optical ... See more keywords
Electrode Droplet Microarray (eDMA): An Impedance Platform for Label‐Free Parallel Monitoring of Cellular Drug Response in Nanoliter Droplets
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402046
Abstract: Label‐free real‐time monitoring of cellular behavior using impedance spectroscopy is important for drug development and toxicological assessments. Parallelization and miniaturization of such experiments are essential for increasing throughput and enabling experiments with low abundant stem… read more here.
Keywords: spectroscopy; real time; drug; monitoring ... See more keywords
Ultrahigh-Sensitivity Sandwiched Plasmon Ruler for Label-Free Clinical Diagnosis.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201905927
Abstract: Optical biosensors, especially those based on plasmonic structures, have emerged recently as a potential tool for disease diagnostics. Plasmonic biosensors have demonstrated impressive benefits for the label-free detection of trace biomarkers in human serum. However,… read more here.
Keywords: sandwiched plasmon; sensitivity; label free; ultrahigh sensitivity ... See more keywords
Immune Profiling and Multiplexed Label‐Free Detection of 2D MXenes by Mass Cytometry and High‐Dimensional Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202205154
Abstract: There is a critical unmet need to detect and image 2D materials within single cells and tissues while surveying a high degree of information from single cells. Here, a versatile multiplexed label‐free single‐cell detection strategy… read more here.
Keywords: label free; cell; mass cytometry; multiplexed label ... See more keywords
Plasmonic Dual‐Gap Nanodumbbells for Label‐Free On‐Particle Raman DNA Assays
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202208250
Abstract: Metal nanostructures with a tunable plasmonic gap are useful for photonics, surface‐enhanced spectroscopy, biosensing, and bioimaging applications. The use of these structures as chemical and biological sensing/imaging probes typically requires an ultra‐precise synthesis of the… read more here.
Keywords: label free; dual gap; gap nanodumbbells; gap ... See more keywords
Ultra‐Fast Label‐Free Serum Metabolic Diagnosis of Coronary Heart Disease via a Deep Stabilizer
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Science"
DOI: 10.1002/advs.202101333
Abstract: Abstract Although mass spectrometry (MS) of metabolites has the potential to provide real‐time monitoring of patient status for diagnostic purposes, the diagnostic application of MS is limited due to sample treatment and data quality/reproducibility. Here,… read more here.
Keywords: diagnosis; ultra fast; deep stabilizer; fast label ... See more keywords
A Versatile, Incubator‐Compatible, Monolithic GaN Photonic Chipscope for Label‐Free Monitoring of Live Cell Activities
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202200910
Abstract: The ability to quantitatively monitor various cellular activities is critical for understanding their biological functions and the therapeutic response of cells to drugs. Unfortunately, existing approaches such as fluorescent staining and impedance‐based methods are often… read more here.
Keywords: label free; cell; chipscope; cell activities ... See more keywords
Fast Label‐Free Metabolic Profile Recognition Identifies Phenylketonuria and Subtypes
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DOI: 10.1002/advs.202305701
Abstract: Phenylketonuria (PKU) is the most common inherited metabolic disease in humans. Clinical screening of newborn heel blood samples for PKU is costly and time‐consuming because it requires multiple procedures, like isotope labeling and derivatization, and… read more here.
Keywords: metabolic profile; label free; subtype identification; pku ... See more keywords
Label‐Free Metal‐Oxide Transistor Biosensors for Metabolite Detection in Human Saliva
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202306038
Abstract: Metabolites are essential molecules involved in various metabolic processes, and their deficiencies and excessive concentrations can trigger significant physiological consequences. The detection of multiple metabolites within a non‐invasively collected biofluid could facilitate early prognosis and… read more here.
Keywords: detection; metal oxide; vit; human saliva ... See more keywords