Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.12.052
Abstract: Background Cellular senescence is a key mechanism that drives age-related diseases, but has yet to be targeted therapeutically in humans. Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal cellular senescence-associated disease. Selectively ablating senescent cells… read more here.
Keywords: label; idiopathic pulmonary; senescence; pulmonary fibrosis ... See more keywords
Open-label pilot study of romiplostim for thrombocytopenia after autologous hematopoietic cell transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007838
Abstract: Key Points • There are no prior prospective studies of thrombopoietin receptor agonists to enhance platelet recovery after auto-HCT.• As studied, romiplostim did not shorten the duration and depth of the platelet nadir, but it… read more here.
Keywords: label pilot; open label; study romiplostim; pilot study ... See more keywords
The Efficacy, Safety, and Tolerability of Probiotics on Depression: Clinical Results From an Open-Label Pilot Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2021.618279
Abstract: Background: A growing body of research has shown that consumption of probiotics can improve symptoms associated with mood and anxiety disorders through activity of the gut-brain axis. However, the effects of probiotics have yet to… read more here.
Keywords: week; pilot study; open label; label pilot ... See more keywords