Der Schein trügt nicht – klinische Evidenz und neue Forschungsansätze zum Open-label-Placebo
Sign Up to like & getrecommendations! Published in 2020 at "Der Nervenarzt"
DOI: 10.1007/s00115-020-00953-6
Abstract: Die Wirkung des Placeboeffekts ist seit mehreren Jahren in experimentellen, klinischen und metaanalytischen Studien belegt. Die bislang als notwendig erachtete Verschleierung der Wirkstofffreiheit einer Placeboanwendung stand bislang der einfachen klinischen Nutzung dieser positiven Effekte sowohl… read more here.
Keywords: die; label placebo; bislang; der ... See more keywords
Even when you know it is a placebo, you experience less sadness: First evidence from an experimental open-label placebo investigation.
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DOI: 10.1016/j.jad.2022.02.043
Abstract: BACKGROUND Recent studies demonstrate substantial effects of deceptive placebo on experimentally induced sadness, even on autonomic activity. Whether deception is necessary, remains to be elucidated. We investigated the effect of an open-label placebo (OLP) treatment,… read more here.
Keywords: mood; group; placebo; induction ... See more keywords
No long-term effects after a 3-week open-label placebo treatment for chronic low back pain: a 3-year follow-up of a randomized controlled trial
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DOI: 10.1097/j.pain.0000000000002752
Abstract: Supplemental Digital Content is Available in the Text. A 3-year follow-up of 89 chronic back pain patients does not support the assumption that a 3-week open-label placebo treatment has long-term effects. read more here.
Keywords: label placebo; week open; placebo treatment; open label ... See more keywords
Open- and Closed-Label Placebo and Nocebo Suggestions About a Sham Transdermal Patch
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DOI: 10.1097/psy.0000000000000862
Abstract: Supplemental digital content is available in the text. ABSTRACT Objective Placebo effects may occur when it is known that an inert substance is given (i.e., open-label placebo). It is not yet clear whether these effects… read more here.
Keywords: label; label placebo; placebo nocebo; open label ... See more keywords
'It's not my greengrocer, it's someone from the medical profession': A qualitative study regarding acceptability of deceptive and open-label placebo prescribing in France.
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DOI: 10.1111/bjhp.12624
Abstract: OBJECTIVES To explore participants' views regarding clinical use of deceptive placebo (DP) and open-label placebo (OLP) treatments. DESIGN Qualitative thematic analysis. METHODS We conducted eight semi-structured interviews with healthy participants in an experimental trial comparing… read more here.
Keywords: placebo prescribing; acceptability; label placebo; placebo ... See more keywords
Open label placebo: can honestly prescribed placebos evoke meaningful therapeutic benefits?
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DOI: 10.1136/bmj.k3889
Abstract: Results from small clinical trials suggesting that placebos can be ethically and effectively used in clinical practice warrant further study, argue Ted Kaptchuk and Franklin Miller read more here.
Keywords: prescribed placebos; placebo honestly; label placebo; honestly prescribed ... See more keywords
Lay perspectives of the open-label placebo rationale: a qualitative study of participants in an experimental trial
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DOI: 10.1136/bmjopen-2021-053346
Abstract: Objectives To analyse participants’ concepts about the open-label placebo (OLP) effect; to explore their views about the discussion points that are applied in conventional OLP trials and to examine their experiences of taking part in… read more here.
Keywords: open label; trial; label placebo; qualitative study ... See more keywords
“Let’s see what happens:”—Women’s experiences of open-label placebo treatment for menopausal hot flushes in a randomized controlled trial
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DOI: 10.1371/journal.pone.0276499
Abstract: Open-label (honestly prescribed) placebos are an ethical way to evoke placebo effects in patients. As part of a mixed-methods study, we conducted in-depth interviews with eight menopausal women who underwent and benefitted from open-label placebo… read more here.
Keywords: open label; placebo treatment; label placebo;