Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06519-0
Abstract: The turnover of brain proteins is critical for organism survival, and its perturbations are linked to pathology. Nevertheless, protein lifetimes have been difficult to obtain in vivo. They are readily measured in vitro by feeding… read more here.
Keywords: mouse brain; amino acids; labeled amino; lifetimes mouse ... See more keywords
Fluorescent-Dye-Labeled Amino Acids for Real-Time Imaging in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28073126
Abstract: Amino acid is the main transport form of reduced nitrogen in plants. To investigate the uptake and source–sink translocation process of plants to help understand their physiological roles and transport mechanisms, we designed and synthesized… read more here.
Keywords: amino acids; labeled amino; dye labeled; arabidopsis thaliana ... See more keywords
Advances in Development of Radiometal Labeled Amino Acid-Based Compounds for Cancer Imaging and Diagnostics
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14020167
Abstract: Radiolabeled biomolecules targeted at tumor-specific enzymes, receptors, and transporters in cancer cells represent an intensively investigated and promising class of molecular tools for the cancer diagnosis and therapy. High specificity of such biomolecules is a… read more here.
Keywords: acid based; amino acid; labeled amino; radiometal labeled ... See more keywords
Recent Advances in 18F-Labeled Amino Acids Synthesis and Application
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102207
Abstract: Radiolabeled amino acids are an important class of agents for positron emission tomography imaging that target amino acid transporters in many tumor types. Traditional 18F-labeled amino acid synthesis strategies are always based on nucleophilic aromatic… read more here.
Keywords: amino acids; 18f labeled; labeled amino; synthesis ... See more keywords