Development of an 18F-Labeled Irreversible Inhibitor of Transglutaminase 2 as Radiometric Tool for Quantitative Expression Profiling in Cells and Tissues.
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DOI: 10.1021/acs.jmedchem.1c00096
Abstract: The transamidase activity of transglutaminase 2 (TGase 2) is considered to be important for several pathophysiological processes including fibrotic and neoplastic tissue growth, whereas in healthy cells this enzymatic function is predominantly latent. Methods that… read more here.
Keywords: 18f labeled; transglutaminase; tgase; expression ... See more keywords