Neopentyl Glycol as a Scaffold to Provide Radiohalogenated Theranostic Pairs of High In Vivo Stability.
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DOI: 10.1021/acs.jmedchem.1c01147
Abstract: The high in vivo stability of 2,2-dihydroxymethyl-3-[18F]fluoropropyl-2-nitroimidazole ([18F]DiFA) prompted us to evaluate neopentyl as a scaffold to prepare a radiotheranostic system with radioiodine and astatine. Three DiFA analogues with one, two, or without a hydroxyl… read more here.
Keywords: neopentyl glycol; vivo stability; labeled neopentyl; high vivo ... See more keywords