IsobaricQuant enables cross‐platform quantification, visualization, and filtering of isobarically‐labeled peptides
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DOI: 10.1002/pmic.202100253
Abstract: In mass spectrometry (MS)‐based quantitative proteomics, labeling with isobaric mass tags such as iTRAQ and TMT can substantially improve sample throughput and reduce peptide missing values. Nonetheless, the quantification of labeled peptides tends to suffer… read more here.
Keywords: quantification; labeled peptides; visualization filtering; quantification visualization ... See more keywords
Predicting fragment intensities and retention time of iTRAQ‐ and TMTPro‐labeled peptides with Prosit‐TMT
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202100257
Abstract: Isobaric labeling increases the throughput of proteomics by enabling the parallel identification and quantification of peptides and proteins. Over the past decades, a variety of isobaric tags have been developed allowing the multiplexed analysis of… read more here.
Keywords: labeled peptides; prosit; itraq tmtpro; prosit tmt ... See more keywords
A quantitation module for isotope-labeled peptides integrated into PatternLab for proteomics.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2019.04.021
Abstract: We present a new module integrated into the widely adopted PatternLab for proteomics to enable analysis of isotope-labeled peptides produced using dimethyl or SILAC. The accurate quantitation of proteins lies within the heart of proteomics;… read more here.
Keywords: module; quantitation; patternlab proteomics; isotope labeled ... See more keywords
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific 68Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors.
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DOI: 10.1021/acs.bioconjchem.2c00272
Abstract: As angiogenesis plays a key role in tumor growth and metastasis, the angiogenic process has attracted scientific interest as a target for diagnostic and therapeutic agents. Factors influencing angiogenesis include the vascular endothelial growth factor… read more here.
Keywords: 68ga labeled; growth; 68ga nodaga; peptide ... See more keywords
Retention Time Prediction for TMT-Labeled Peptides in Proteomic LC-MS Experiments.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00833
Abstract: We present the first detailed study of chromatographic behavior of peptides labeled with tandem mass tags (TMT and TMTpro) in 2D LC for proteomic applications. Carefully designed experimental procedures have permitted generating data sets of… read more here.
Keywords: retention; retention time; tmt; labeled peptides ... See more keywords
Radionuclide-Labeled Peptides for Imaging and Treatment of CXCR4- Overexpressing Malignant Tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026619666190201094952
Abstract: Malignant tumors are a major cause of death. The lack of methods that provide an early diagnosis and adequate treatment of cancers is the main obstacle to precision medicine. The C-X-C chemokine receptor 4 (CXCR4)… read more here.
Keywords: radionuclide labeled; treatment; peptides imaging; labeled peptides ... See more keywords