Strategies for Covalent Labeling of Long RNAs
Sign Up to like & getrecommendations! Published in 2021 at "Chembiochem"
DOI: 10.1002/cbic.202100161
Abstract: The introduction of chemical modifications into long RNA molecules at specific positions for visualization, biophysical investigations, diagnostic and therapeutic applications still remains challenging. In this review, we present recent approaches for covalent internal labeling of… read more here.
Keywords: strategies covalent; covalent labeling; long rnas; biology ... See more keywords
Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1100
Abstract: Abstract Labeling of long RNA molecules in a site-specific yet generally applicable manner is integral to many spectroscopic applications. Here we present a novel covalent labeling approach that is site-specific and scalable to long intricately… read more here.
Keywords: single molecule; site specific; site; spectroscopy ... See more keywords