Membrane Protein Binding Interactions Studied in Live Cells via Diethylpyrocarbonate Covalent Labeling Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05616
Abstract: Membrane proteins are vital in the human proteome for their cellular functions and make up a majority of drug targets in the U.S. However, characterizing their higher-order structures and interactions remains challenging. Most often membrane… read more here.
Keywords: labeling mass; mass spectrometry; covalent labeling; membrane ... See more keywords
Quantitative Analysis of Protein Covalent Labeling Mass Spectrometry Data in the Mass Spec Studio.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b01625
Abstract: Covalent labeling with mass spectrometry (CL-MS) provides a direct measure of the chemical and structural features of proteins with the potential for resolution at the amino-acid level. Unfortunately, most applications of CL-MS are limited to… read more here.
Keywords: mass spectrometry; covalent labeling; analysis; mass ... See more keywords