Articles with "labeling reagents" as a keyword



New Set of Isobaric Labeling Reagents for Quantitative 16Plex Proteomics.

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Published in 2023 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.3c00235

Abstract: Peptide labeling by isobaric tags is a powerful approach for the relative quantitative analysis of proteomes in multiple groups. There has been a revolution in the innovation of new isobaric reagents; however, great effort is… read more here.

Keywords: set isobaric; labeling reagents; ibt 16plex; reagents quantitative ... See more keywords

Structure–Activity Relationship of Metabolic Sialic Acid Inhibitors and Labeling Reagents

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Published in 2022 at "ACS Chemical Biology"

DOI: 10.1021/acschembio.1c00868

Abstract: Sialic acids cap the glycans of cell surface glycoproteins and glycolipids. They are involved in a multitude of biological processes, and aberrant sialic acid expression is associated with several pathologies, such as cancer. Strategies to… read more here.

Keywords: sialic acid; labeling reagents; structure activity; acid ... See more keywords

Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors

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Published in 2024 at "RSC Advances"

DOI: 10.1039/d4ra07074g

Abstract: The endogenous neurosteroids dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate (PS) are allosteric modulators of γ-aminobutyric acid type A (GABAA) and N-methyl-d-aspartate (NMDA) type glutamate receptors. Analogues of these endogenous steroid sulfates can be either positive… read more here.

Keywords: allosteric modulators; photoaffinity labeling; steroid sulfates; labeling reagents ... See more keywords