Immunogenicity of recombinant Lactobacillus casei‐expressing F4 (K88) fimbrial adhesin FaeG in conjunction with a heat‐labile enterotoxin A (LTAK63) and heat‐labile enterotoxin B (LTB) of enterotoxigenic Escherichia coli as an oral adjuvant in mice
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DOI: 10.1111/jam.13352
Abstract: The aims of this study were to develop an effective oral vaccine against enterotoxigenic Escherichia coli (ETEC) infection and to design new and more versatile mucosal adjuvants. read more here.
Keywords: heat labile; escherichia coli; labile enterotoxin; enterotoxigenic escherichia ... See more keywords
Heat-Labile Enterotoxin-Induced PERK-CHOP Pathway Activation Causes Intestinal Epithelial Cell Apoptosis
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DOI: 10.3389/fcimb.2017.00244
Abstract: Enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea among children and travelers in developing countries, and heat-labile enterotoxin (LT) is one of the most important virulence factors. The pathogenesis of and virulence factors… read more here.
Keywords: intestinal epithelial; epithelial cell; apoptosis; heat labile ... See more keywords
Both LTA and LTB Subunits Are Equally Important to Heat-Labile Enterotoxin (LT)-Enhanced Bacterial Adherence
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DOI: 10.3390/ijms24021245
Abstract: There is increasing evidence indicating that the production of heat-labile enterotoxin (LT) enhances bacterial adherence within in vitro and in vivo models. However, which subunit plays the main role, and the precise regulatory mechanisms remain… read more here.
Keywords: adherence; bacterial adherence; enhanced bacterial; subunit ... See more keywords
Dendritic Cell-Mediated Mechanisms Triggered by LT-IIa-B5, a Mucosal Adjuvant Derived from a Type II Heat-Labile Enterotoxin of Escherichia coli.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.1611.11072
Abstract: Mucosal tissues are the initial site through which most pathogens invade. As such, vaccines and adjuvants that modulate mucosal immune functions have emerged as important agents for disease prevention. Herein, we investigated the immunomodulatory mechanisms… read more here.
Keywords: mucosal adjuvant; escherichia coli; mucosal; heat labile ... See more keywords
Expression of Heat-labile Enterotoxin of Escherichia coli in Biolistic Transformed Hairy Roots of Daucus carota L
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DOI: 10.5530/pj.2019.11.x
Abstract: Production of antigens and antibodies in plant provide a potential approach for the development of vaccines for oral delivery.1 Traditional vaccines are facing challenges like storage, distribution and administration but recently their safety and effectiveness… read more here.
Keywords: expression heat; hairy roots; escherichia coli; enterotoxin escherichia ... See more keywords