Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108181
Abstract: SUMMARY Hemopexin (Hx) is a scavenger of labile heme. Herein, we present data defining the role of tumor stroma-expressed Hx in suppressing cancer progression. Labile heme and Hx levels are inversely correlated in the plasma… read more here.
Keywords: hemopexin; heme; cancer; growth metastases ... See more keywords
Molecular Imaging of Labile Heme in Living Cells Using a Small Molecule Fluorescent Probe.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c08485
Abstract: Labile heme (LH) is a complex of Fe(II) and protoporphyrin IX, an essential signaling molecule in various biological systems. Most of the subcellular dynamics of LH remain unclear because of the lack of efficient chemical… read more here.
Keywords: molecule; labile heme; living cells; fluorescent probe ... See more keywords