Effects of Cannabinoid Agonists and Antagonists on Sleep in Laboratory Animals.
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DOI: 10.1007/978-3-030-61663-2_7
Abstract: The cannabinoids are a family of chemical compounds that can be either synthesized or naturally derived. These compounds have been shown to modulate a wide variety of biological processes. In this chapter, the studies detailing… read more here.
Keywords: laboratory animals; cannabinoid agonists; agonists antagonists; effects cannabinoid ... See more keywords
Effects of Light at Night on Laboratory Animals and Research Outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Behavioral Neuroscience"
DOI: 10.1037/bne0000252
Abstract: Light has substantial influences on the physiology and behavior of most laboratory animals. As such, lighting conditions within animal rooms are potentially significant and often underappreciated variables within experiments. Disruption of the light/dark cycle, primarily… read more here.
Keywords: research; light night; laboratory; laboratory animals ... See more keywords
Alternative methods for killing laboratory animals: Summary of a published advisory report by the Netherlands national Committee for the protection of animals used for scientific purposes and for education (NCad)
Sign Up to like & getrecommendations! Published in 2017 at "Laboratory Animals"
DOI: 10.1177/0023677217695435
Abstract: Webiste: https://english.ncadierproevenbeleid.nl/advice/ documents/reports/16/9/15/ncad-opinion-on-alternativekilling-methods-for-laboratory-animals In September 2015, the Dutch Minister of Agriculture requested the NCad (Netherlands National Committee for the protection of animals used for scientific purposes) to advise on methods of killing for laboratory animals… read more here.
Keywords: netherlands national; killing laboratory; national committee; methods killing ... See more keywords
On determining sample size in experiments involving laboratory animals
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DOI: 10.1177/0023677217738268
Abstract: Scientists using laboratory animals are under increasing pressure to justify their sample sizes using a “power analysis”. In this paper I review the three methods currently used to determine sample size: “tradition” or “common sense”,… read more here.
Keywords: sample size; size; laboratory animals; power analysis ... See more keywords
Microbiota, laboratory animals, and research
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DOI: 10.1177/0023677219844538
Abstract: Back in the 19th century, working with laboratory rodents was dangerous. There was a certain risk of catching hazardous zoonoses such as Yersinia pestis, Leptospira, Salmonella, and Streptobacillus moniliformis. It was, therefore, common, to decontaminate… read more here.
Keywords: research; disease; rodent; century ... See more keywords
Impulse for animal welfare outside the experiment
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DOI: 10.1177/0023677219891754
Abstract: Animal welfare is a growing societal concern and the well-being of animals used for experimental purposes is under particular scrutiny. The vast majority of laboratory animals are mice living in small cages that do not… read more here.
Keywords: animal welfare; outside experiment; laboratory animals; welfare ... See more keywords
Report from the 11th edition of the World Congress on Alternatives and Animal Use in the Life Sciences (WC11)
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory Animals"
DOI: 10.1177/00236772211064174
Abstract: In August 2021, the WC11 was performed as a virtual event with the main theme ‘3Rs in transition: from development to application’. The event focused on the discrepancy between progress in cutting-edge nonanimal methods and… read more here.
Keywords: report 11th; 11th edition; non animal; laboratory animals ... See more keywords
Pathological analysis of batch safety testing of veterinary vaccines using small laboratory animals
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Toxicologic Pathology"
DOI: 10.1293/tox.2020-0078
Abstract: Batch safety tests (BSTs) of veterinary vaccines are conducted using small laboratory animals to assure the safety of vaccines according to several criteria, including clinical signs and change in body weight. Although the latter is… read more here.
Keywords: small laboratory; safety; laboratory animals; veterinary vaccines ... See more keywords
Role of Nuclear Imaging to Understand the Neural Substrates of Brain Disorders in Laboratory Animals: Current Status and Future Prospects
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2020.596509
Abstract: Molecular imaging, which allows the real-time visualization, characterization and measurement of biological processes, is becoming increasingly used in neuroscience research. Scintigraphy techniques such as single photon emission computed tomography (SPECT) and positron emission tomography (PET)… read more here.
Keywords: current status; brain disorders; nuclear imaging; role ... See more keywords
Safety and Pharmacokinetics of the Substance of the Anti-Smallpox Drug NIOCH-14 after Oral Administration to Laboratory Animals
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DOI: 10.3390/v15010205
Abstract: Background: Since most of the modern human population has no anti-smallpox immunity, it is extremely important to develop and implement effective drugs for the treatment of smallpox and other orthopoxvirus infections. The objective of this… read more here.
Keywords: substance; safety; administration; laboratory animals ... See more keywords