Effect of cholesterol on the lactosylceramide domains in phospholipid bilayers.
Sign Up to like & getrecommendations! Published in 2022 at "Biophysical journal"
DOI: 10.1016/j.bpj.2022.02.037
Abstract: Lactosylceramide (LacCer) in the plasma membranes of immune cells is an important lipid for signaling in innate immunity through the formation of LacCer-rich domains together with cholesterol (Cho). However, the properties of the LacCer domains… read more here.
Keywords: cho; popc; properties laccer; laccer domains ... See more keywords
Plasma sphingolipid abnormalities in neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0279315
Abstract: Background In recent years, there has been increasing evidence that several lipid metabolism abnormalities play an important role in the pathogenesis of neurodegenerative diseases. However, it is still unclear which lipid metabolism abnormalities play the… read more here.
Keywords: metabolism; laccer; disease; diseases plasma ... See more keywords
Dynamic assembly and interaction of glycosphingolipids in cholesterol-containing model membranes
Sign Up to like & getrecommendations! Published in 2023 at "Pure and Applied Chemistry"
DOI: 10.1515/pac-2023-0204
Abstract: Abstract Glycosphingolipids (GSLs) in the mammalian plasma membrane are essential for various biological events that occur on cell membranes by forming glycolipid-rich membrane domains, such as lipid rafts. Lactosylceramide (LacCer) forms a highly ordered phase… read more here.
Keywords: interaction; laccer; cholesterol containing; dynamic assembly ... See more keywords
Convergence: Lactosylceramide-Centric Signaling Pathways Induce Inflammation, Oxidative Stress, and Other Phenotypic Outcomes
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041816
Abstract: Lactosylceramide (LacCer), also known as CD17/CDw17, is a member of a large family of small molecular weight compounds known as glycosphingolipids. It plays a pivotal role in the biosynthesis of glycosphingolipids, primarily by way of… read more here.
Keywords: convergence lactosylceramide; inflammation; laccer; laccer synthase ... See more keywords