Vacuolar H+-ATPase dysfunction rescues intralumenal vesicle cargo sorting in yeast lacking PI(3,5)P2 or Doa4.
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DOI: 10.1242/jcs.258459
Abstract: Endosomes undergo a maturation process highlighted by a reduction in lumenal pH, a conversion of surface markers that prime endosome-lysosome fusion, and the sequestration of ubiquitinated transmembrane protein cargoes within intralumenal vesicles (ILVs). We investigated… read more here.
Keywords: lacking doa4; cargo sorting; vacuolar atpase; yeast lacking ... See more keywords