Articles with "lacking kras" as a keyword



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Survival of pancreatic cancer cells lacking KRAS function

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Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-00942-5

Abstract: Activating mutations in the proto-oncogene KRAS are a hallmark of pancreatic ductal adenocarcinoma (PDAC), an aggressive malignancy with few effective therapeutic options. Despite efforts to develop KRAS-targeted drugs, the absolute dependence of PDAC cells on… read more here.

Keywords: pdac cells; lacking kras; pancreatic cancer; cancer cells ... See more keywords