Electrochemical characterization of cefadroxil β-lactam antibiotic and Cu(II) complex formation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2019.04.077
Abstract: Abstract The electrochemical behaviour of cefadroxil, a first-generation β-lactam antibiotic, was studied at glassy carbon electrodes in aqueous media over a wide range of pH. The first oxidation process is of the phenol moiety and… read more here.
Keywords: characterization cefadroxil; lactam antibiotic; formation; cefadroxil lactam ... See more keywords
Thermostable β-Lactamase Mutant with Its Active Site Conjugated with Fluorescein for Efficient β-Lactam Antibiotic Detection
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.9b02211
Abstract: Monitoring the β-lactam antibiotic level has been an important task in food industry and clinical practice. Here, we report the development of a fluorescent PenP β-lactamase, PenP-E166Cf/N170Q, for efficient β-lactam antibiotic detection. It was constructed… read more here.
Keywords: lactam antibiotic; e166cf n170q; antibiotic detection; penp e166cf ... See more keywords
Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-38984-y
Abstract: In persons with cystic fibrosis (CF), decreased airway microbial diversity is associated with lower lung function. Conflicting data exist on the impact of short-term antibiotics for treatment of acute pulmonary exacerbations. However, whether differences in… read more here.
Keywords: lactam antibiotic; antibiotic exposure; diversity; beta lactam ... See more keywords
Implementation of EMR-based standardized antibiotic desensitization protocols and its impact on providers.
Sign Up to like & getrecommendations! Published in 2021 at "Allergy and asthma proceedings"
DOI: 10.2500/aap.2021.42.200115
Abstract: Background: As desensitization protocols become more readily available and published, more institutions are implementing them and searching for ways to streamline the process. There have been no published studies to date on the effect that… read more here.
Keywords: lactam antibiotic; antibiotic desensitization; desensitization protocols; desensitization ... See more keywords
Molecular Mechanism of the β-Lactamase Mediated β-Lactam Antibiotic Resistance of Pseudomonas aeruginosa Isolated From a Chinese Teaching Hospital
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.855961
Abstract: Pseudomonas aeruginosa can cause infections in the blood, lungs (pneumonia), or other parts of the body after surgery. To investigate the molecular characteristics of β-lactam antibiotic resistance of P. aeruginosa isolated from a hospital population… read more here.
Keywords: antibiotic resistance; pseudomonas aeruginosa; resistance; lactam antibiotic ... See more keywords
Why We May Need Higher Doses of Beta-Lactam Antibiotics: Introducing the ‘Maximum Tolerable Dose’
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11070889
Abstract: The surge in antimicrobial resistance and the limited availability of new antimicrobial drugs has fueled the interest in optimizing antibiotic dosing. An ideal dosing regimen leads to maximal bacterial cell kill, whilst minimizing the risk… read more here.
Keywords: beta lactam; toxicity; lactam antibiotic; maximum tolerable ... See more keywords