Efficacy of non‐beta lactam antibiotics for prevention of cesarean delivery wound infections: 14
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2017.08.094
Abstract: expression of CCL3 (a Th1 chemoattractant) and higher expression of CCL2 (a Th2 chemoattractant) at 1 and 2 wpi. In vitro, cervical epithelial cells infected with Ct expressed IL-1b when treated with vehicle control. P4… read more here.
Keywords: antibiotics prevention; lactam antibiotics; non beta; efficacy non ... See more keywords
pMEX01, a 70 kb plasmid isolated from Escherichia coli that confers resistance to multiple β-lactam antibiotics
Sign Up to like & getrecommendations! Published in 2018 at "Brazilian Journal of Microbiology"
DOI: 10.1016/j.bjm.2017.11.002
Abstract: Multidrug-resistant microorganisms are of great concern to public health. Genetic mobile elements, such as plasmids, are among the most relevant mechanisms by which bacteria achieve this resistance. We obtained an Escherichia coli strain CM6, isolated… read more here.
Keywords: lactam antibiotics; escherichia coli; pmex01 plasmid; resistance multiple ... See more keywords
Kinetic model development for α-amino ester hydrolase (AEH) catalyzed synthesis of β-lactam antibiotics
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.131816
Abstract: Abstract α-Amino ester hydrolases (AEH) are a class of enzymes highly specific for catalyzing the synthesis and hydrolysis of amides and esters of α-amino acids. They are particularly promising catalyst candidates as an alternative to… read more here.
Keywords: substrate inhibition; synthesis; aeh catalyzed; model ... See more keywords
Lysozyme Counteracts β-Lactam Antibiotics by Promoting the Emergence of L-Form Bacteria
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.01.021
Abstract: Summary β-lactam antibiotics inhibit bacterial cell wall assembly and, under classical microbiological culture conditions that are generally hypotonic, induce explosive cell death. Here, we show that under more physiological, osmoprotective conditions, for various Gram-positive bacteria,… read more here.
Keywords: lactam antibiotics; lysozyme counteracts; form; counteracts lactam ... See more keywords
β-Lactam antibiotics and antibiotic resistance in Asian lakes and rivers: An overview of contamination, sources and detection methods.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.116624
Abstract: Lakes and rivers are sources of livelihood, food and water in many parts of the world. Lakes provide natural resources and valuable ecosystem services. These aquatic ecosystems are also vulnerable to known and new environmental… read more here.
Keywords: lactam antibiotics; lakes rivers; resistance; antibiotic resistance ... See more keywords
A quinoline-based FtsZ inhibitor for the study of antimicrobial activity and synergistic effects with β-lactam antibiotics.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2018.07.005
Abstract: The antibacterial activity and the synergistic effect with β-lactam antibiotics of a new 1-methylquinolinium iodide derivative were investigated. The experimental results indicate that the compound possesses a strong antibacterial activity against a panel of bacteria… read more here.
Keywords: ftsz; lactam antibiotics; activity synergistic; compound ... See more keywords
Evanescent Wave Optical Fiber Sensors Using Enzymatic Hydrolysis on Nanostructured Polyaniline for Detection of β-Lactam Antibiotics in Food and Environment.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c04169
Abstract: β-Lactam antibiotics such as penicillins and cephalosporins are extensively used for human infection therapy. Consistent unintended exposure to these antibiotics via food and water is known to promote antibiotic-resistant bacterial pathogenesis with high morbidity and… read more here.
Keywords: detection; lactam antibiotics; enzymatic hydrolysis; antibiotics food ... See more keywords
Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past To Help Discover Long-Acting Oral Drugs in the Future
Sign Up to like & getrecommendations! Published in 2018 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.8b00160
Abstract: β-Lactams represent perhaps the most important class of antibiotics yet discovered. However, despite many years of active research, none of the currently approved drugs in this class combine oral activity with long duration of action.… read more here.
Keywords: past help; lactam antibiotics; help discover; pharmacokinetics lactam ... See more keywords
Teaching a New Dog Old Tricks: Ultrafast Liquid Chromatography/Tandem-Mass Spectrometry Analysis of Nine ß-Lactam Antibiotics for Improved Therapeutic Drug Monitoring
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000001007
Abstract: Supplemental Digital Content is Available in the Text. Background: Therapeutic drug monitoring (TDM) of β-lactam antibiotics provides critical knowledge in hospital intensive care unit environments to support dosing within the narrow window between therapeutic failure… read more here.
Keywords: chromatography tandem; liquid chromatography; therapeutic drug; lactam antibiotics ... See more keywords
Stability of 10 Beta-Lactam Antibiotics in Human Plasma at Different Storage Conditions.
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic drug monitoring"
DOI: 10.1097/ftd.0000000000001100
Abstract: BACKGROUND Recently, several studies have assessed the effects of therapeutic drug monitoring of frequently prescribed beta-lactam antibiotics, for which they were quantified in human plasma samples. Beta-lactams are considered unstable, leading to extra challenges in… read more here.
Keywords: beta lactam; human plasma; plasma samples; lactam antibiotics ... See more keywords
In vitro Susceptibility to β-Lactam Antibiotics and Viability of Neisseria gonorrhoeae Strains Producing Plasmid-Mediated Broad- and Extended-Spectrum β-Lactamases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.1101/2022.03.11.483876
Abstract: N. gonorrhoeae strains producing plasmid-mediated broad- and extended-spectrum β-lactamases (ESBLs) have been obtained in vitro and studied for their viability and susceptibility to β-lactam antibiotics. The artificial pblaTEM-1 and pblaTEM-20 plasmids were constructed by site-directed… read more here.
Keywords: plasmid; gonorrhoeae strains; pblatem; lactam antibiotics ... See more keywords