Studies on daptomycin lactam‐based analogues
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Peptide Science"
DOI: 10.1002/psc.3430
Abstract: Herein, we report the synthesis and antibacterial evaluation of a series of daptomycin lactam‐based analogues. As compared with daptomycin, the daptomycin analogue with singly modified lactam has an eightfold increase in its minimum inhibitory concentration… read more here.
Keywords: antibacterial activity; based analogues; lactam based; daptomycin lactam ... See more keywords
Surgical site infection rates are higher among elective colorectal surgery patients receiving non-beta-lactam-based antimicrobial prophylaxis: A retrospective chart review.
Sign Up to like & getrecommendations! Published in 2022 at "Infection control and hospital epidemiology"
DOI: 10.1017/ice.2022.192
Abstract: Abstract We compared the odds of acquiring surgical site infection (SSI) for clean-contaminated colorectal surgeries between intravenous β-lactam–based prophylaxis (BLP) versus alternative antimicrobial prophylaxis (AAP). We calculated the odds of acquiring an SSI using logistic… read more here.
Keywords: infection; lactam based; site infection; antimicrobial prophylaxis ... See more keywords
Structural and Electronic Origin of Bis-Lactam-Based High-Performance Organic Thin-Film Transistors.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.8b20168
Abstract: We describe herein the comprehensive theoretical and experimental studies on the transistor mobility of organic semiconductors by correlating a two-dimensional (2D) intermolecular interaction with thin-film morphology and the electronic coupling structure. We developed a novel… read more here.
Keywords: lactam based; lactam; bis lactam; thin film ... See more keywords
Discovery and Optimization of Seven-Membered Lactam-Based Compounds to Phenocopy the Inhibition of the Aurora Kinase B.
Sign Up to like & getrecommendations! Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00098
Abstract: We used mechanism-informed phenotypic screening to identify and optimize compounds that phenocopy the genetic depletion of the mitotic aurora kinase B (AURKB) kinase. After assaying nine aryl fused seven-membered lactam compounds, we identified a hit… read more here.
Keywords: membered lactam; aurora kinase; seven membered; lactam based ... See more keywords
Fused polycyclic lactam-based π-conjugated polymers for efficient nonfullerene organic solar cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Materials Chemistry A"
DOI: 10.1039/d3ta01127e
Abstract: The development of high-performance wide-bandgap polymers has attracted significant attention in recent non-fullerene organic solar cells (NF-OSCs) research, as the expansion of the options of polymer donors that are appropriately... read more here.
Keywords: organic solar; solar cells; lactam based; polycyclic lactam ... See more keywords