Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.04.053
Abstract: Emergence of antibiotic-resistant bacteria constitutes an increasing threat to human health. For example, treatment options for Staphylococcus aureus infections is declining with the worldwide spreading of highly virulent community-associated methicillin-resistant S. aureus (CA-MRSA) strains. Anti-virulence therapy… read more here.
Keywords: agrc; autoinducing peptides; lactam hybrid; solonamide autoinducing ... See more keywords