Sign Up to like & get
recommendations!
0
Published in 2021 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.0c00863
Abstract: ConspectusEver since the first β-lactam antibiotic, penicillin, was introduced into the clinic over 70 years ago, resistance has been observed because of the presence of β-lactamase enzymes, which hydrolyze the β-lactam ring of β-lactam antibiotics.…
read more here.
Keywords:
gram negative;
chemistry;
lactamase enzymes;
resistance ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2021.2023645
Abstract: Abstract An increasing global health challenge is antimicrobial resistance. Bacterial infections are often treated by using β-lactam antibiotics. But several resistance mechanisms have evolved in clinically mutated bacteria, which results in resistance against such antibiotics.…
read more here.
Keywords:
lactamase enzymes;
class lactamase;
resistance;
lactamase ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2022 at "Microbiology"
DOI: 10.1099/mic.0.001217
Abstract: The discovery of penicillin by Alexander Fleming marked a new era for modern medicine, allowing not only the treatment of infectious diseases, but also the safe performance of life-saving interventions, like surgery and chemotherapy. Unfortunately,…
read more here.
Keywords:
epidemiology;
medicine;
biogenesis lactamase;
lactamase enzymes ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12040744
Abstract: Outer membrane vesicles (OMVs) are nanoparticles released by Gram-negative bacteria, which contain different cargo molecules and mediate several biological processes. Recent studies have shown that OMVs are involved in antibiotic-resistance (AR) mechanisms by including β-lactamase…
read more here.
Keywords:
omvs isolated;
lactamase enzymes;
outer membrane;
vesicles omvs ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15040476
Abstract: β-lactam antibiotics (BLAs) are crucial molecules among antibacterial drugs, but the increasing emergence of resistance to them, developed by bacteria producing β-lactamase enzymes (BLEs), is becoming one of the major warnings to the global public…
read more here.
Keywords:
lactamase enzymes;
enzymes inhibitors;
class;
antibiotics lactamase ... See more keywords