Lactate dehydrogenase predicting mortality in patients with aneurysmal subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51650
Abstract: Lactate dehydrogenase (LDH) has been reported to be associated with outcomes after surgery in patients with aneurysmal subarachnoid hemorrhage (aSAH), but it is unclear if this is independent from other biomarkers and across all aSAH… read more here.
Keywords: aneurysmal subarachnoid; subarachnoid hemorrhage; patients aneurysmal; mortality patients ... See more keywords
Targeting lactate dehydrogenase A (LDHA) exerts antileukemic effects on T‐cell acute lymphoblastic leukemia
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DOI: 10.1002/cac2.12080
Abstract: T‐cell acute lymphoblastic leukemia (T‐ALL) is an uncommon and aggressive subtype of acute lymphoblastic leukemia (ALL). In the serum of T‐ALL patients, the activity of lactate dehydrogenase A (LDHA) is increased. We proposed that targeting… read more here.
Keywords: cell acute; lymphoblastic leukemia; acute lymphoblastic; lactate dehydrogenase ... See more keywords
Clinical value of jointly detection serum lactate dehydrogenase/pleural fluid adenosine deaminase and pleural fluid carcinoembryonic antigen in the identification of malignant pleural effusion
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22106
Abstract: Limited data are available for the diagnostic value, and for the diagnostic sensitivity and specificity of joint detection of serum lactate dehydrogenase (sLDH)/pleural fluid adenosine deaminase (pADA) and pleural fluid carcinoembryonic antigen (pCEA) in malignant… read more here.
Keywords: detection serum; fluid; pleural fluid; lactate dehydrogenase ... See more keywords
Bioactivity screening, extraction, and separation of lactate dehydrogenase inhibitors from Polygala tenuifolia Willd. based on a hyphenated strategy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201601216
Abstract: Stroke is the second leading cause of death worldwide. Lactate dehydrogenase inhibitors are currently widely used in the treatment of ischemic stroke, and natural products are considered promising sources of lactate dehydrogenase inhibitors. In this… read more here.
Keywords: extraction; lactate dehydrogenase; dehydrogenase inhibitors; separation ... See more keywords
Time- and Dose-Dependent Toxicity Studies in 3D Cultures Using a Luminescent Lactate Dehydrogenase Assay.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1162-3_8
Abstract: Three-dimensional (3D) in vitro systems closely resemble tissue microenvironments and provide predictive models for studying cytotoxic drug responses. The ability to capture the kinetic profiles of such responses in a dynamic and noninvasive way can… read more here.
Keywords: time dose; toxicity; luminescent lactate; dose dependent ... See more keywords
Identification of nucleic acid aptamers against lactate dehydrogenase via SELEX and high-throughput sequencing
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03397-2
Abstract: Nucleic acid aptamers are small fragments of DNA or RNA molecules binding specifically to targets, which can be obtained through in vitro screening via systematic evolution of ligands by exponential enrichment (SELEX). Lactate dehydrogenase (LDH)… read more here.
Keywords: throughput sequencing; ldh; lactate dehydrogenase; nucleic acid ... See more keywords
Major role of lactate dehydrogenase D-LDH1 for the synthesis of lactic acid in Fructobacillus tropaeoli CRL 2034
Sign Up to like & getrecommendations! Published in 2020 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-020-10776-9
Abstract: The enzymes D- and L-lactate dehydrogenase are involved in the reduction of pyruvate to D(+)- and L(−)-lactate, respectively. The fig-origin strain Fructobacillus tropaeoli CRL 2034 produces D- and L-lactic acids in a 9:1 ratio. In… read more here.
Keywords: crl 2034; acid; lactate dehydrogenase; tropaeoli crl ... See more keywords
Serum lactate dehydrogenase level is associated with in-hospital mortality in critically Ill patients with acute kidney injury
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DOI: 10.1007/s11255-021-02792-z
Abstract: Sixty percent of critically ill patients suffer from acute kidney injury (AKI) and 12% of them require renal replacement therapy during their ICU stay. However, we lack effective biomarkers to predict the mortality of critically… read more here.
Keywords: hospital mortality; ill patients; mortality; critically ill ... See more keywords
Serum lactate dehydrogenase level as a possible predictor of treatment preference in psoriasis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2021.07.007
Abstract: BACKGROUND The efficacy of small molecule inhibitors for intracellular signal mediators varies among the individuals, and their mechanism of action is broad. A phosphodiesterase 4 inhibitor apremilast shows a dramatic effect on a certain proportion… read more here.
Keywords: treatment; level; psoriasis; lactate dehydrogenase ... See more keywords
Impact of serum lactate dehydrogenase on the short-term prognosis of COVID-19 with pre-existing cardiovascular diseases
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DOI: 10.1016/j.jjcc.2021.12.014
Abstract: Background Patients with coronavirus disease 2019 (COVID-19) and underlying cardiovascular comorbidities have poor prognoses. Our aim was to identify the impact of serum lactate dehydrogenase (LDH), which is associated with mortality in acute respiratory distress… read more here.
Keywords: impact serum; serum lactate; covid; lactate dehydrogenase ... See more keywords
Exertional myalgia, contractures and annular erythema in a patient with muscle lactate dehydrogenase (LDH) deficiency
Sign Up to like & getrecommendations! Published in 2018 at "Neuromuscular Disorders"
DOI: 10.1016/j.nmd.2017.09.013
Abstract: • A novel missense mutation in the lactate dehydrogenase A gene (LDHA) was identified in a Chinese family with glycogenosis type XI. read more here.
Keywords: dehydrogenase; contractures annular; exertional myalgia; annular erythema ... See more keywords