The effect of general anaesthetics on brain lactate release
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2020.173188
Abstract: The effects of anaesthetic agents on brain energy metabolism may explain their shared neurophysiological actions but remain poorly understood. The brain lactate shuttle hypothesis proposes that lactate, provided by astrocytes, is an important neuronal energy… read more here.
Keywords: lactate release; brain lactate; lactate; anaesthetic agents ... See more keywords
Discovery of Mitochondrial Complex I Inhibitors as Anticancer and Radiosensitizer Drugs Based on Compensatory Stimulation of Lactate Release
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DOI: 10.3390/cancers14215454
Abstract: Simple Summary To identify inhibitors of mitochondrial respiration as potential anticancer drugs is not an easy matter since cancer cells cultured as monolayers may escape by shifting their metabolic preference toward the use of glycolysis.… read more here.
Keywords: mitochondrial complex; cancer cells; cancer; lactate release ... See more keywords