Solid-Phase-Based Synthesis of Lactazole-Like Thiopeptides.
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DOI: 10.1021/acs.orglett.2c02870
Abstract: A strategy for the synthesis of de novo discovered lactazole-like thiopeptides is reported. The approach revolves around a convergent and scalable preparation of the central triheterocyclic amino acid and its utilization in Fmoc solid-phase peptide… read more here.
Keywords: like thiopeptides; lactazole like; synthesis; phase based ... See more keywords