Pulmonary artery catheter usage in diagnosis of Shoshin beriberi presented with unexplained lactic acidosis.
Sign Up to like & getrecommendations! Published in 2023 at "ESC heart failure"
DOI: 10.1002/ehf2.14374
Abstract: Wet beriberi is a rare but fatal disease in modern society. The nonspecific clinical manifestations, including symptoms of heart failure and recalcitrant lactic acidosis, can prevent timely diagnosis. The use of a pulmonary artery catheter… read more here.
Keywords: lactic acidosis; artery catheter; beriberi; pulmonary artery ... See more keywords
Murburn precepts for lacticâacidosis, Cori cycle, and Warburg effect: Interactive dynamics of dehydrogenases, protons, and oxygen
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30661
Abstract: It is unresolved why lactate is transported to the liver for further utilization within the physiological purview of Cori cycle, when muscles have more lactate dehydrogenase (LDH) than liver. We point out that the answer… read more here.
Keywords: protons oxygen; cori cycle; warburg effect; lactate ... See more keywords
A severe linezolidâinduced rhabdomyolysis and lactic acidosis in Leigh syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12328
Abstract: To the Editor, Recently, De Vries et al. reported the results of a Delphi-based workshop to develop consensus guidelines for physicians prescribing drugs for patients with mitochondrial diseases. The pharmacological management of these subjects is… read more here.
Keywords: acidosis; leigh syndrome; lactic acidosis; rhabdomyolysis ... See more keywords
Prevalence and risk factors of lactic acidosis in children with acute moderate and severe asthma, a prospective observational study
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Pediatrics"
DOI: 10.1007/s00431-020-03834-x
Abstract: Lactic acidosis is a common complication of status asthmaticus in adults. However, data is sparse in children. The aim of this study was to describe the prevalence and risk factors for lactic acidosis in children… read more here.
Keywords: acidosis; factors lactic; lactic acidosis; risk factors ... See more keywords
Combined metformin-associated lactic acidosis and euglycemic ketoacidosis
Sign Up to like & getrecommendations! Published in 2017 at "Wiener Klinische Wochenschrift"
DOI: 10.1007/s00508-017-1251-6
Abstract: SummaryBackgroundIn renal failure metformin can lead to lactic acidosis. Additional inhibition of hepatic gluconeogenesis by accumulation of the drug may aggravate fasting-induced ketoacidosis. We report the occurrence of metformin-associated lactic acidosis (MALA) with concurrent euglycemic… read more here.
Keywords: metformin associated; lactic acidosis; ketoacidosis; associated lactic ... See more keywords
The Association between Metformin Therapy and Lactic Acidosis
Sign Up to like & getrecommendations! Published in 2019 at "Drug Safety"
DOI: 10.1007/s40264-019-00854-x
Abstract: There is increasing evidence to suggest that therapeutic doses of metformin are unlikely to cause lactic acidosis. The aims of this research were (1) to formally evaluate the association between metformin therapy and lactic acidosis… read more here.
Keywords: acidosis; metformin associated; lactic acidosis; association ... See more keywords
Metformin Lactic Acidosis: should we still be afraid?
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2019.107879
Abstract: Metformin, the first choice drug for type 2 diabetes treatment in all stages of therapy, and one of the most widely prescribed anti-hyperglycemic agent worldwide, represents a rare example of an old drug which continues… read more here.
Keywords: acidosis; lactic acidosis; acidosis still; still afraid ... See more keywords
Long-Standing Hypokalemia and Lactic Acidosis as the Primary Presentation of Mitochondrial Myopathy
Sign Up to like & getrecommendations! Published in 2020 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2020.01.021
Abstract: INTRODUCTION M itochondrial disorders are rare diseases that are caused by mutations of either mitochondrial DNA or nuclear mitochondrial genes. The clinical manifestations of mitochondrial disorders can vary widely and there is typically a lack… read more here.
Keywords: acidosis; presentation; hypokalemia lactic; lactic acidosis ... See more keywords
Severe type B lactic acidosis and insulin-resistant hyperglycemia related to cadaveric kidney transplantation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of clinical anesthesia"
DOI: 10.1016/j.jclinane.2017.11.024
Abstract: Lactic acidosis, increased lactate levels N2 mmol/L with a high anion gapmetabolic acidosis, commonly occurs due to hypoperfusion/hypoxia (type A) but may also arise due to other causes, often overlooked, such as thiamine deficiency (type… read more here.
Keywords: acidosis; cadaveric kidney; lactic acidosis; hyperglycemia ... See more keywords
Improved lactate control with dichloroacetate in a case with severe neonatal lactic acidosis due to MTFMT mitochondrial translation disorder
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2020.100616
Abstract: Mitochondrial methionyl-tRNA formyltransferase (MTFMT) is a nuclear-encoded gene that produces a protein involved in mitochondrial translation. MTFMT formylates a portion of Met-tRNAMet, which allows for translation initiation of mitochondrial mRNA. Mutations in this gene have… read more here.
Keywords: lactic acidosis; lactate; dichloroacetate; translation ... See more keywords
Lactic acidosis induces resistance to the pan-Akt inhibitor uprosertib in colon cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Cancer"
DOI: 10.1038/s41416-020-0777-y
Abstract: Background Akt signalling regulates glycolysis and drives the Warburg effect in cancer, thus decreased glucose utilisation is a pharmacodynamic marker of Akt inhibition. However, cancer cells can utilise alternative nutrients to glucose for energy such… read more here.
Keywords: lactic acidosis; pan akt; resistance; cancer cells ... See more keywords